Swimming into your heart: Using zebrafish to study vascular defects resulting from embryonic alcohol exposure

In my study, I will be using zebrafish embryos as a model of Fetal Alcohol Spectrum Disorder. The specific transgenic strain I am researching, Tg-Fli-EGFP, has blood vessel and heart cells labeled with a fluorescent protein EGFP, allowing detailed observation of angiogenesis and the embryo vasculature. By exposing zebrafish embryos of this line to varying concentrations of alcohol at different key points post-fertilization, I will be able to examine developmental changes if they occur. If changes are observed, a potential future study could focus on treatment solutions for FASD.

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